Vaccines through the cheak

Faglige nøgleord: pharmacy, viral infections, global health, vaccines, pandemics, mRNA vaccines

Oplæg tilgængeligt på: Engelsk og tysk

I am pharmacist by training and my research is in the development of a vaccine platform intended for application through the cheak (as opposed to the conventional delivery route -  the muscle). Specifically, I am using the mRNA vaccine platform, which was successfully used during the COVID-19 pandemics. Conventional (intramuscular) immunizations are effective when it comes to systemic (whole-body) immunity. They induce the production of antibodies that circulate in the blood and protect the human body if a virus is encountered. However, they do not induce a strong local (mucosal) immune response, aka immune response at the entry sites for the virus. Airborne viral infections are mostly described by a viral particle entering the body through the nose or the mouth. Therefore, a stronger immune protection at those entry sites would first prevent the virus from entering and secondly reduce the spread of viral particles by secretes. 
Having a strong relation to global health and preventions of disease spread is the main reason why the project is relevant to the society. 
I went to a German Highschool in Sofia, Bulgaria. Afterwards I moved to Germany, Heidelberg, to study pharmacy. I graduated as a registered pharmacist. As part of my journey to get the license to be a pharmacist, I worked 6 months in a community pharmacy. Alongside my academic journey I gained experience and insights in biotechnology, gene editing and drug delivery. The latter turned out to be my main area of interest. That is how I landed at MIT, the USA, where I completed my Master thesis in pharmaceutical technology. I worked on developing thermostable mRNA vaccines, that can be stored at room temperature and do not require the highly environmentally burdensome cold chain. The next step was finding a PhD position, which happened to be at DTU and SSI (Statens Serum Institute) and that is how I ended up in Denmark. 
I have been part in various programmes for engaging academically with highschool students and I really enjoyed the work with younger people and aspiring scientist. 
I would like to make a blend of a pptx slides and chalk talk. My experience so far has shown me that for some key concepts it is actually beneficial to slow down and use a white/blackboard which allows for the students to follow the flow of thoughts better. Furthermore, I can incorporate exercise task of different complexity based on the 3 levels of knowledge examination (Reproduction of facts, Explanation of concepts and finally, Application of concepts on new questions).
I speak 5 languages (Bulgarian, German, Russian, Turkish, English) and my Danish is getting steadily better (B1-B2), so I am able to communicate on daily topics, yet I don't feel comfortable to compile a nice talk 100% in Danish. Though I have quite some vocabulary in the area as I discuss such topics with my colleagues in Danish. 

Fag og faglige nøgleord

Dette oplæg passer for eksempel godt til:

 

Biologi

Bioteknologi

Kemi

 

Nøgleord:

  • pharmacy
  • viral infections
  • global health
  • vaccines
  • pandemics
  • mRNA vaccines

Sprog og form på besøget

Klassebesøg eller foredrag?

Dette oplæg kan tilpasses enten til en klasse (op til ca. 28 elever), hvor den ph.d.-studerende har mulighed for at have dialog med eleverne, eller til en større forsamling, så det får karakter af foredrag.

 

Sprog?

Dette oplæg er tilgængeligt på engelsk og tysk.

 

Digitalt eller fysisk besøg?

Den ph.d.-studerende kommer gerne ud på jeres skole til et fysisk besøg, men møder jer også digitalt via platformen Zoom, hvis I foretrækker det.

Øvrig information

Dette oplæg er ikke tilgængeligt i januar 2027

 

Er du interesseret i dette oplæg?

Kontakt

Taja Andersen Brenneche
Kommunikationsmedarbejder
AKM
45 25 10 57
https://bookphd.dtu.dk/find-foredrag/alle-foredrag-liste/vaccines-through-the-cheak
15 JUNI 2026